Jan M. SkotheimPrincipal InvestigatorEducation : Ph.D. Applied Mathematics University of Cambridge 2004Postdoctoral Research : Rockefeller University w/F. Cross & E.D. SiggiaEmail : skotheim Interests : Jan is interested in all aspects of cell cycle control. Two key questions facing the laboratory are 1. How do cells compute their own size? 2. Are systems-level properties, such as transcriptional feedback circuits, conserved throughout eukaryotes?

Jan M. Skotheim

Principal Investigator

Education : Ph.D. Applied Mathematics University of Cambridge 2004

Postdoctoral Research : Rockefeller University w/F. Cross & E.D. Siggia

Email : skotheim

Interests : Jan is interested in all aspects of cell cycle control. Two key questions facing the laboratory are 1. How do cells compute their own size? 2. Are systems-level properties, such as transcriptional feedback circuits, conserved throughout eukaryotes?

Mardo KoivomagiPostdoctoral researcher October 2013-University of Tartu, Ph.D., BiochemistryEmail: mardok Interests: The biochemistry of cell size control

Mardo Koivomagi

Postdoctoral researcher October 2013-

University of Tartu, Ph.D., Biochemistry

Email: mardok

Interests: The biochemistry of cell size control

Evgeny ZatulovskiyPostdoctoral researcher May 2014-University of Cambridge, Ph.D., Cell Biology Email: evgeny Interests : Dynamic signal processing and decision making in mammalian cell cycle control

Evgeny Zatulovskiy

Postdoctoral researcher May 2014-

University of Cambridge, Ph.D., Cell Biology
Email: evgeny
Interests : Dynamic signal processing and decision making in mammalian cell cycle control

Crystal Tsui

PhD Student in Bioengineering 2021-

Education: MIT, BS chemical engineering & Biology

Interests: Cell size and genome size

Shuyuan ZhangPosition: Postdoctoral researcher 2018-Education: Ph.D. UT Southwestern Medical Center, Liver ploidy and liver cancerInterest: Cell cycle and cell size regulation in mammalian liveEmail: zhangsy

Shuyuan Zhang

Position: Postdoctoral researcher 2018-

Education: Ph.D. UT Southwestern Medical Center, Liver ploidy and liver cancer

Interest: Cell cycle and cell size regulation in mammalian live

Email: zhangsy

Jordan XiaoPh.D. student, June 2020-BA Berkeley PhysicsEmail: jyxiao Interests: Systems/mechanisms that coordinate size sensing and the cell cycle

Jordan Xiao

Ph.D. student, June 2020-

BA Berkeley Physics

Email: jyxiao

Interests: Systems/mechanisms that coordinate size sensing and the cell cycle

Jacob KimGraduate student, Chemical and Systems Biology, September 2018-Education: Williams College, B.A. Biology w/ conc. in Biochem/Mol BioEmail: jmhkimInterests: control and coordination of cell cycle and cell size

Jacob Kim

Graduate student, Chemical and Systems Biology, September 2018-

Education: Williams College, B.A. Biology w/ conc. in Biochem/Mol Bio

Email: jmhkim

Interests: control and coordination of cell cycle and cell size

Mike LanzPosition: Postdoctoral researcher 2019-Education: PhD - Cornell University, BS - Penn StateEmail: mikelanz Interests: How do cells know how big they are?

Mike Lanz

Position: Postdoctoral researcher 2019-

Education: PhD - Cornell University, BS - Penn State

Email: mikelanz

Interests: How do cells know how big they are?

Lucas Fuentes Valenzuela

PhD student Electrical Engineering 2022-

Education: MS U. Liege Engineering Physics

Interests: Deciphering the molecular basis of cellular dynamics, from models and experiments

Matthew SwafferPosition: Postdoctoral researcher 2017-present.Education: Ph.D. (Cell & Molecular Biology) - The Francis Crick Institute, UK. M.A. (Natural Sciences) - University of Cambridge, UK.Interest: How do cells coordinate gene expression with cell size and growth.Email: swaffer

Matthew Swaffer

Position: Postdoctoral researcher 2017-present.

Education: Ph.D. (Cell & Molecular Biology) - The Francis Crick Institute, UK. M.A. (Natural Sciences) - University of Cambridge, UK.

Interest: How do cells coordinate gene expression with cell size and growth.

Email: swaffer

Cecelia BrownGraduate student, Biology, June 2019-  Education: B.S. Biology, San Jose State University  Email: ceceliaf  Interests: Understanding how a cell commits to division and the molecular mechanisms involved in that decision.

Cecelia Brown

Graduate student, Biology, June 2019-

Education: B.S. Biology, San Jose State University

Email: ceceliaf

Interests: Understanding how a cell commits to division and the molecular mechanisms involved in that decision.

Shicong (Mimi) XiePostdoctoral researcher August 2016-MIT, Ph.D., Computational Systems BiologyEmail: xiesInterests: The cell cycle in vivo

Shicong (Mimi) Xie

Postdoctoral researcher August 2016-

MIT, Ph.D., Computational Systems Biology

Email: xies

Interests: The cell cycle in vivo

Dong Shin (Chris) YouGraduate Student, July 2020-Swarthmore College, BA Biology & Political ScienceInterests: Regulation of biosynthesis with cell sizeEmail: cdsyou

Dong Shin (Chris) You

Graduate Student, July 2020-

Swarthmore College, BA Biology & Political Science

Interests: Regulation of biosynthesis with cell size

Email: cdsyou


Alumni

Postdocs

Andreas Doncic, now Assistant Prof. of Cell Biology at UT Southwestern (deceased 2018)

Jennifer Ewald, now Assistant Prof. University of Tübingen

Kurt Schmoller, now Assistant Prof. Helmholtz Institute, Munich

Ali Shariati, now Assistant Professor of Biomelecular Engineering at UCSC

David Jukam, biotech

Graduate Students

Umut Eser, Ph.D. Applied Physics, 2013 Thesis : Spatio-temporal regulation of cell cycle transcription.
Subsequent position : Postdoc with Stirling Churchman at Harvard Medical School now Director of Data Science at Cellarity

Amy Johnson, Ph.D. Biology, 2014 Thesis : Onset of Cdk2 activity determines passage through the restriction point in primary cells.
Subsequent position : Biotech industry, scientist at Regeneron.

Amanda Amodeo, Ph.D. Biology, 2014 co-mentor Aaron Straight Thesis : Histone titration by DNA sets the threshold for the mid-blastula transition in Xenopus Subsequent position : Lewis-Sigler Fellow (PI) Princeton University

Oguzhan Atay, Ph.D. Biology, 2016, Thesis: Not Isolated, But Still Insulated: Switch-like Transitions Modularize Biological Networks.
Subsequent position: founder of Billiontoone Biotech company

Clayton Schwarz, Ph.D. Biology, 2018, Thesis: A precise Cdk activity threshold determines passage through the restriction point. Subsequent position: postdoc with Prof. Eric Siggia, The Rockefeller University.

Jon Turner, Ph.D. Biology, 2018, Thesis: Distinct mechanisms of multisite phosphorylation of the transcriptional inhibitor Whi5 regulate the budding yeast cell cycle. Subsequent position: biotech scientist with enEvolve

Devon Chandler-Brown, Ph.D. Biology, 2019, Thesis: Regulation of Cell Size and the Size Dependence of Gene Expression. Subsequent position: biotech scientist with Billiontoone Inc.

Daniel Berensen, MD/Ph.D.Biology, 2019, Thesis: Measurement and maintenance of human cell size. Subsequent position: Medical student.

Ben Reyes Topacio, Ph.D. Biology, 2020, Thesis: The mechanism of helix-based docking between Cyclin D-Cdk4,6 and the retinoblastoma protein

Undergraduates and Technicians

Franklin Caval-Holme : Stanford Biology Undergraduate 2010-13 Dean's Award for signficant academic achievement for an undergraduate Senior Thesis : Whi5 Inheritance Influences the Size-Threshold for Cell Cycle Commitment (Start) in the S.Cerevisiae Cell Cycle Subsequent position : applying for graduate school

Melody Falleur-Fettig : Life Science Technician II 2008-2012, founding member of Skotheim lab

Taryn Malia Sumabat : Stanford Biology Undergraduate 2009-2011 Subsequent position : Teaching with the Princeton in Asia program / Now graduate student at Berkeley, MCB Senior Thesis : Examining variability of mammalian cell cycle timing and dynamics at single-cell resolution

Elena Kassianidou : Stanford Biomechanical Engineering Undergraduate 2009-2011 Subsequent position : Graduate Student at Berkeley Bioengineering Senior Thesis : Substrate stiffness affects the proliferation rate of fibroblast and epithelial cells in a cell type dependent manner

Phil Shiu : Stanford Biology Undergraduate 2008-2010 Subsequent position : Graduate student at Harvard MCB w/Craig Hunter Senior Thesis : Does Saccharomyces cerevisiae require positive feedback at mitotic entry? The role of early and late mitotic cyclins in activating CLB2 transcription.

Avi Robinson-Mosher : Visiting Graduate Student 2009-2010 (Stanford Ph.D Computer Science) Subsequent position : Postdoc w/ Pam Silver @ Harvard Systems Biology

Chris Aakre : Life Science Technician II 2008-2009 Subsequent position : MIT graduate student Microbiology program w/Mike Laub

Hnin Ookhin : Stanford Biomechanical Engineering Undergraduate 2009-2011 Elliot Lui : Stanford Biomechanical Engineering Undergraduate 2010-2011 XiaoSong Mu : Stanford Biology Undergraduate summer 2012 Devin King : Stanford Biology Undergraduate 2012 Ryoko Hamaguchi : Stanford Biology Undergraduate summer 2012